Development of a multiplexed fluorescent immunoassay for the quantitation of antibody responses to group A streptococci

TB Martins, NH Augustine, HR Hill - Journal of immunological methods, 2006 - Elsevier
The host immunologic response to group A streptococcal infections gives rise to numerous
antibodies directed against cellular and extracellular bacterial antigens. For determining
individual immune status, or studying the pathogenesis of group A streptococcal associated
diseases, such as acute rheumatic fever (ARF), an assay capable of determining antibodies
responses to multiple antigens would be of great advantage. We have developed a
microsphere based, multiplexed immunoassay for the simultaneous quantitation of …
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